Nucleic Acid-Based Hydrogel Development Services
Combining the intrinsic biological properties of nucleic acids with their unique programmability, nucleic acid-based hydrogels are considered to be the next generation of smart biomaterials for bioanalytical and biomedical research. Matexcel, as a preferred partner in hydrogel development, has a long history of helping our customers develop nucleic acid-based hydrogels with superior performance, and we are confident that our extensive experience and advanced platform will provide the best service to meet each of their needs.
Advantages of Nucleic Acid-Based Hydrogel
Since the discovery of the DNA double helix structure, interest in DNA has expanded from its genetic role to applications in nanotechnology and biomaterials science. In particular, DNA-based hydrogels possess numerous advantageous features such as flexibility, stability, precise programmability, stimulus responsiveness, and ease of synthesis and modification. In addition, functional nucleic acids (FNAs) allow the construction of hydrogels based on aptamers, DNAzymes, i-motif nanostructures, siRNA, and CpG oligodeoxynucleotides to provide additional functions such as catalytic activity, molecular recognition, and disease diagnosis and treatment, making them revolutionary biomaterials for bioanalytical and biomedical applications. In addition, despite the disadvantages of RNA such as instability and difficulty in predicting structure, there are already cases for constructing RNA hydrogels with desired biological functions and mechanical properties through sequence-oriented modular design. Until now, nucleic acid-based hydrogels have proven to have powerful potential for a variety of applications, including biosensing, controlled drug release, environmental analysis, cell adhesion, and targeted cancer therapy.
Fig. 1 Formation of Y-shaped DNA branches and DNA hydrogel by PCR. (Li J., et al., 2016)
Our Services
Matexcel leverages our advanced technology and extensive experience in hydrogel development to help our customers break through all the challenges in nucleic acid-based hydrogel research and development. Our customized nucleic acid-based hydrogel development services include, but are not limited to, the following.
If you are interested in additional hydrogel development services, please fill out our online inquiry form and tell us more about your project.
Why Partner with Matexcel?
- As a world leader in hydrogel development, Matexcel has the experienced experts and advanced platform to provide quality nucleic acid-based hydrogel customized development services to our customers.
- Our common dream is to create stronger functional hydrogels to benefit more fields. Our knowledgeable and dedicated team of scientists will provide you with the most valuable advice and technical support at every stage of your project.
- Our extensive background in hydrogels allows us to provide insight into the design of nucleic acid-based hydrogel development solutions as well as the latest technology trends and innovative global expertise.
Want to learn more?
Matexcel has a pioneering technology platform and innovative thinking in the field of hydrogel research and development. Based on a team of professional scientists and years of experience, we have successfully established a full range of integrated services for hydrogel development, ranging from hydrogel formulation development to hydrogel analysis and characterization. Our scientists are confident to provide you with high-quality nucleic acid-based hydrogel development services. If you are interested in our services, please fill out the online inquiry form and tell us more about your project.
Reference
- Li J.; et al. Functional nucleic acid-based hydrogels for bioanalytical and biomedical applications. Chem Soc Rev. 2016, 45(5):1410-31.