DNA Hydrogel Development Services
DNA hydrogels are three-dimensional reticulated polymeric materials formed mainly by the involvement of DNA, while the perfect blend of its DNA biological properties with the mechanical properties of its own framework has made it one of the most sought-after emerging functional polymer materials in recent years. As a pioneer in the development of hydrogels, Matexcel is committed to developing customized DNA hydrogels for our global customers to facilitate their needs in a wide range of applications.
Advantages of DNA Hydrogel
Deoxyribonucleic acid (DNA) not only serves as the material basis for biological inheritance, but also shows great potential for the construction of biomaterials due to its programmability, biocompatibility, functional versatility, and biodegradability. Different DNA sequences have different effects on the denseness of the formed DNA hydrogels, and we can design and synthesize nucleic acids with certain sequences by molecular biology techniques to achieve precise preparation of DNA nanostructures in a programmable and predictable manner. In addition, DNA can be modified with many functional groups, such as acrylates, amino groups, carboxyl groups, and thiols, etc. These unique properties allow DNA to bind to some polymers or nanomaterials through covalent, electrostatic, and hydrogen bonds, which further expands the application of DNA hydrogels. Therefore, during the preparation of DNA hydrogels, the types of hydrogel components and cross-linking methods can be flexibly adjusted according to the specific needs of downstream applications to present DNA hydrogels with different shapes, sizes and functional properties.
Fig. 1 Schematic of magnetic driven DNA hydrogel synthesis. (Wang Z., et al., 2022)
Applications of DNA Hydrogel in the Biomedical Field
DNA Hydrogel is suitable for a wide range of biomedical applications due to its excellent biocompatibility, biodegradability, catalytic activity, fundamental programmability, therapeutic potential and molecular recognition capabilities.
- Used in drug loading and sustained release.
- Used in targeted gene therapy.
- Used in the field of biosensing for the detection of substances such as heavy metals and toxins.
- Used in cell culture.
- Used to construct cell-free protein production platforms.
Our Services
Matexcel leverages our advanced technology and extensive experience in hydrogel development to help our customers break through all the challenges in DNA hydrogel research and development. Our customized DNA hydrogel development services include, but are not limited to, the following.
- DNA Hydrogel Formulation Design Services: We provide customized DNA hydrogel formulation design services, adjusting the hydrogel component type, nucleic acid sequence, cross-linking method, reaction temperature, and other conditions according to the different requirements of downstream applications for hydrogel mechanical and functional properties.
- DNA Hydrogel Modification Services: We can develop customized DNA hydrogel modification solutions by modifying the DNA with functional groups or incorporating other functional materials to further enhance its functional properties.
- DNA Hydrogel Analysis and Characterization Services: We provide a full range of analysis and characterization services in the development of DNA hydrogels, as well as efficacy testing services for hydrogel samples.
Process of Our Service
Want to Learn More?
As a forward-thinking hydrogel development company, Matexcel has gained extensive experience in the completion of different projects, during which we have received wide recognition and praise from our customers. By combining cutting-edge technology with proprietary innovation, our scientists are dedicated to providing a full range of services related to DNA hydrogel development. If you are interested in our services, please fill out the online inquiry form and tell us more about your project.
Reference
- Wang Z.; et al. Design and application of stimuli-responsive DNA hydrogels: A review. Mater Today Bio. 2022, 16:100430.