Silk Fibroin-Based Hydrogel Development Services

In recent years, hydrogels prepared from silk fibroin have received extensive research attention due to their biocompatibility, biosafety, controlled degradation, and integration with other materials. In view of the broad application scenarios of silk fibroin-based hydrogels in biomedical and other fields, Matexcel is committed to providing custom development services for silk fibroin-based hydrogels to our global customers. Our team of dedicated scientists and advanced technology platforms will significantly facilitate your hydrogel research projects.

Advantages and Challenges of Silk Fibroin-Based Hydrogel

Silk fibroin is the main component of silk and possesses impressive biocompatibility, controlled degradability, and ease of processing. Due to its unique functional properties, silk fibroin-based hydrogel is considered to be an excellent candidate for many applications. However, the conventional silk fibroin-based hydrogel suffers from the disadvantages of irreversible mechanical properties, lack of energy dissipation mechanism, poor responsiveness to the application environment, insufficient adhesion to the solid-state interface, and lack of intelligent behavior, which hinder the full utilization of silk fibroin-based hydrogel. Therefore, there is a need to design and modulate the molecular level of the multi-scale structure of silk fibroin in order to create new functional silk fibroin-based hydrogel with excellent properties such as high strength, self-healing ability, and environmental stimulus responsiveness for application scenarios in different fields.

Fig. 1 The schematic diagram of silk fibroin hydrogels formed by physical cross-linking. (Zheng H., et al., 2021)

Applications of Silk Fibroin-Based Hydrogel

In recent years, silk fibroin-based hydrogels with excellent functional properties such as injectability, self-healing, adhesion, electrical conductivity, and responsiveness to environmental stimuli have been developed. The complementary strategy of the multiple components and synergy of functionalities allow silk fibroin-based hydrogels to meet the requirements of a wide range of applications.

Our Services

Matexcel leverages our advanced technology and extensive experience in hydrogel development to help our customers break through all the challenges in silk fibroin-based hydrogel research and development. Our customized silk fibroin-based hydrogel development services include, but are not limited to, the following.

• Silk Fibroin-Based Hydrogel Formulation Design Services: We provide customized silk fibroin-based hydrogel formulation design services to adjust the polymer concentration, cross-linking method, reaction temperature, pH and other conditions of the hydrogel according to the different requirements of downstream applications for the mechanical and functional properties of hydrogels.
• Silk Fibroin-Based Hydrogel Modification Services: We can develop tailor-made modification solutions to modify and optimize the original properties of silk fibroin-based hydrogels, such as improving their mechanical properties, electrical conductivity, adhesive properties, and self-healing capabilities, according to the requirements of various performance parameters for downstream applications.
• Silk Fibroin-Based Hydrogel Analysis and Characterization Services: We provide a full range of analysis and characterization services in the development of silk fibroin-based hydrogels, as well as efficacy testing services for hydrogel samples.

Process of Our Service

Want to Learn More?

As a leading global provider of hydrogel R&D services, Matexcel has accumulated extensive experience in the completion of different projects, during which we have received wide recognition and praise from our customers. We have completed several challenging protein-based hydrogel development services projects. We are proud to be able to provide our valued customers with high quality services to eliminate the difficulties in your projects. If you are interested in our services, please fill out the online inquiry form and tell us more about your project.

Reference

1. Zheng H.; Zuo B. Functional silk fibroin hydrogels: preparation, properties and applications. J Mater Chem B. 2021, 9(5):1238-1258.