Serum Albumin-Based Hydrogel Development Services
Albumin-based hydrogels are an under-explored biomaterial and they have great potential as customizable, xeno-free, and transplantable constructs for tissue engineering and regenerative medicine. As a preferred partner in the field of hydrogel development, Matexcel is committed to providing customized development services for serum albumin-based hydrogel to customers worldwide. Our experienced team of scientists and experts will provide you with professional technical support and advice at all stages of your project.
Advantages of Serum Albumin-Based Hydrogel
Albumin is an endogenous, non-glycosylated protein produced primarily by hepatocytes in the liver and is the most abundant plasma protein in mammals. With a physiological half-life of approximately 19 days, albumin stabilizes important proteins, metal ions, hormones, nanoparticles, and drugs in vitro and in vivo. In addition, albumin is responsive to pH and temperature and readily forms gels under specific conditions. This versatility, stability, and low-concentration gelation ability, together with its cheapness and biocompatibility, make albumin a highly promising biomaterial for applications. Currently, the development of albumin-based hydrogel materials with individualized characteristics and intrinsic biocompatibility in the field of tissue engineering and regenerative medicine is attractive and urgent.
Fig. 1 Ribbon diagrams showing the partial denaturation of N-form to F-form albumin, protein aggregation, and hydrogel formation. (Ong J., et al., 2019)
Applications of Serum Albumin-Based Hydrogel in the Biomedical Field
Based on the special properties of serum albumin, such as non-immunogenicity, sustainability, low cost, biodegradability, and biocompatibility, albumin-based hydrogels are increasingly in demand in the biomedical field, especially in the field of tissue engineering beyond the treatment of various diseases.
- Used in bone and cartilage regeneration.
- Used in skin regeneration and wound healing.
- Used for tissue engineering and regenerative medicine applications in heart, liver, lung, breast, nerve, and other tissues and organs.
- Used to control drug release and delivery.
Our Services
Matexcel leverages our advanced technology and extensive experience in hydrogel development to help our customers break through all the challenges in serum albumin-based hydrogel research and development. Our customized serum albumin-based hydrogel development services include, but are not limited to, the following.
- Serum Albumin-Based Hydrogel Formulation Design Services: We provide customized serum albumin-based hydrogel formulation design services to adjust the polymer concentration, cross-linking method, reaction temperature, pH, and other conditions of the hydrogel according to the different requirements of downstream applications for the mechanical and functional properties of hydrogels.
- Serum Albumin-Based Hydrogel Modification Services: We can develop customized modification solutions to modify and optimize the original properties of serum albumin-based hydrogel, such as modifying its mechanical properties, biodegradability, pore size, and biochemical properties, depending on the requirements of various performance parameters for downstream applications.
- Serum Albumin-Based Hydrogel Analysis and Characterization Services: We provide a full range of analysis and characterization services in the development of serum albumin-based hydrogels, as well as efficacy testing services for hydrogel samples.
Process of Our Service
Want to Learn More?
As a leading global provider of hydrogel R&D services, Matexcel has accumulated extensive experience in the completion of different projects, during which we have received wide recognition and praise from our customers. We have completed several challenging protein-based hydrogel development services projects. We are proud to be able to provide our valued customers with high quality services to eliminate the difficulties in your projects. If you are interested in our services, please fill out the online inquiry form and tell us more about your project.
Reference
- Ong J.; et al. Albumin-based hydrogels for regenerative engineering and cell transplantation. Biotechnol Bioeng. 2019, 116(12):3457-3468.