Poly(vinyl Alcohol)-Based Hydrogel Development
Poly(vinyl alcohol)-based hydrogel is recognized as a promising material for a wide range of biomedical applications due to its excellent properties. As a pioneer in hydrogel development, Matexcel is committed to developing customized poly(vinyl alcohol)-based hydrogels for our global customers to meet their needs in a wide range of applications.
Introduction to Poly(vinyl Alcohol)-Based Hydrogel
Poly(vinyl alcohol) (PVA), a water-soluble and biocompatible synthetic polymer, contains a large number of hydroxyl functional groups that can be cross-linked to form hydrogels. Due to its chemical stability, non-toxicity, biocompatibility, biological aging resistance, water absorption capacity, and easy processing, PVA -based hydrogel plays a unique role in many fields such as agriculture, industry, and medicine. PVA -based hydrogels can usually be prepared by physical cross-linking, chemical cross-linking, or radiation cross-linking methods. Despite its many advantages, the development of poly(vinyl alcohol)-based hydrogels still faces some challenges, such as low mechanical strength, crosslinking efficiency susceptible to contaminants, and high production costs. Nevertheless, ongoing research and development efforts are aimed at addressing these limitations and improving the performance of PVA-based hydrogels.
Fig. 1 Schematic synthesis of PVA hydrogel with high strength and toughness. (Chen Y., et al., 2022)
Applications of Poly(vinyl Alcohol)-Based Hydrogel in Biomedicine
Poly(vinyl Alcohol)-based hydrogels have found numerous applications due to their unique properties, such as biocompatibility, biodegradability, and versatility in response to different stimuli.
- Tissue Engineering: PVA-based hydrogels are widely used as scaffolds for cell culture and tissue regeneration in the field of tissue engineering.
- Drug Delivery: PVA-based hydrogels have been developed as drug delivery systems due to their ability to release drugs in a controlled manner, their biocompatibility, and their biodegradability.
- Biomedical Implants: PVA-based hydrogels have been developed as biodegradable implants for various medical applications, such as osteoarthritis treatment and drug delivery.
- Medical Devices: PVA-based hydrogels have been used as medical devices for various applications, such as contact lenses, wound dressings, and drug delivery systems.
- Smart Hydrogels: PVA-based hydrogels can respond to different stimuli, such as temperature, pH, and ionic strength, making them ideal for smart drug delivery systems and soft robotics.
Our Services
Matexcel leverages our advanced technology and extensive experience in hydrogel development to help our customers break through all the challenges in poly(vinyl alcohol)-based hydrogel research and development. Our customized poly(vinyl alcohol)-based hydrogel development services include, but are not limited to, the following.
- Poly(vinyl Alcohol)-Based Hydrogel Formulation Design Services
We provide customized poly(vinyl alcohol)-based hydrogel formulation design services to adjust the permeability, elasticity, molecular diffusivity, modulus, equilibrium water content, and degradation rate of hydrogels according to the different requirements of downstream applications for the physicochemical and functional properties of hydrogels. - Poly(vinyl Alcohol)-Based Hydrogel Modification Services
We can provide customized poly(vinyl alcohol)-based hydrogel modification services based on specific customer needs. For example, by modifying the surface of poly(vinyl alcohol)-based hydrogel to improve its biocompatibility, biodegradability and hydrophilicity. - Poly(vinyl Alcohol)-Based Hydrogel Analysis and Characterization Services
We provide a full range of analysis and characterization services in the development of poly(vinyl alcohol)-based hydrogels, as well as efficacy testing services for hydrogel samples.
Process of Our Service
Want to Learn More?
Matexcel is a professional hydrogel development company with a high degree of professionalism and quality service that has established the company as a leader in the industry. We have a lot of mature and reproducible experience in the development of various types of hydrogels and are confident to help you solve all your problems in poly(vinyl alcohol)-based hydrogel development. If you are interested in our services, please fill out the online inquiry form and tell us more about your project.
Reference
- Chen Y., et al. Synthesis and properties of Poly(vinyl alcohol) hydrogels with high strength and toughness. Polymer Testing. 2022, 108: 107516.