Poly(N,N-dimethylacrylamide)-Based Hydrogel Development
Poly(N,N-dimethylacrylamide) (PDMA) -based hydrogel is a type of hydrogel that is widely used in various fields, including biomedical and environmental engineering. PDMA-based hydrogel is a polymer composed of N,N-dimethylacrylamide monomers, which can form a three-dimensional cross-linked network structure when polymerized. As a pioneer in hydrogel development, Matexcel is committed to developing customized poly(N,N-dimethylacrylamide)-based hydrogels for our global customers to meet their needs in a wide range of applications.
Introduction of Poly(N,N-dimethylacrylamide)-Based Hydrogel
Poly(N,N-dimethylacrylamide)-based hydrogels are a class of polymer-based hydrogels synthesized from N,N-dimethylacrylamide monomer, which are widely used in various biomedical applications due to their unique properties of biocompatibility, biodegradability, and tunable mechanical properties. Typically, PDMA-based hydrogel is prepared by free radical polymerization of the N,N-dimethylacrylamide monomers, which can be initiated by different types of initiators, including thermal initiators, photoinitiators, and redox initiators. The polymerization process can be carried out in the presence or absence of cross-linkers to control the swelling and mechanical properties of the resulting hydrogel. Moreover, PDMA-based hydrogel can be modified by incorporating various functional groups, such as carboxylic acid, amino, and hydroxyl groups, to enhance its chemical and physical properties, as well as to allow for specific interactions with biological molecules. Additionally, the mechanical properties of PDMA hydrogel can be tuned by adjusting the polymerization conditions, such as the monomer concentration, cross-linker concentration, and polymerization time. In conclusion, PDMA-based hydrogels are versatile and promising biomaterials with a wide range of potential applications in various fields due to their unique properties.
Fig. 1 FESEM images of poly (N, N-dimethylacrylamide) pure hydrogel. (Shahid Bashir., et al., 2021)
Applications of Poly(N,N-dimethylacrylamide)-Based Hydrogel in Biomedicine
Poly(N,N-dimethylacrylamide)-based hydrogels are known for their high water content, biocompatibility, and biodegradability, which make them suitable for various applications in drug delivery, tissue engineering, and other biomedical fields.
- Drug Delivery: PDMA hydrogel has a unique property of swelling and de-swelling based on the temperature changes. It can release the drugs in a controlled and sustained manner, making it an ideal material for drug delivery systems.
- Tissue Engineering: PDMA hydrogel can be used as a scaffold to support the growth of various types of cells. Its biocompatibility, porosity, and mechanical properties make it a suitable material for tissue engineering applications.
- Biosensors: PDMA hydrogel can be functionalized with biomolecules and used as a sensing element in biosensors. The hydrogel can detect changes in pH, temperature, and other environmental factors and provide real-time feedback.
- Wound Healing: PDMA hydrogel can be used in wound healing applications. Its biocompatibility and ability to release drugs in a controlled manner can aid in the healing process.
- Anti-fouling Coatings: PDMA hydrogel can be used as an anti-fouling coating, preventing the adhesion of proteins or other biomolecules on surfaces such as medical devices or water treatment membranes.
Our Services
Matexcel leverages our advanced technology and extensive experience in hydrogel development to help our customers break through all the challenges in poly(N,N-dimethylacrylamide)-based hydrogel research and development. Our customized poly(N,N-dimethylacrylamide)-based hydrogel development services include, but are not limited to, the following.
- Poly(N,N-dimethylacrylamide)-Based Hydrogel Formulation Design Services
We offer a customized poly(N,N-dimethylacrylamide)-based hydrogel formulation design service where we consider the specific requirements and specifications of your hydrogel application, such as the required mechanical properties, porosity, and swelling behavior, to ensure that the poly(N,N-dimethylacrylamide)-based hydrogel formulation is tailored specifically for your particular application. - Poly(N,N-dimethylacrylamide)-Based Hydrogel Modification Services
We offer modification services for poly(N,N-dimethylacrylamide)-based hydrogels, including the use of chemical modification, physical modification, and biomodification techniques to modify their properties or introduce new functionality to suit specific application requirements. - Poly(N,N-dimethylacrylamide)-Based Hydrogel Analysis and Characterization Services
We provide a full range of analysis and characterization services in the development of poly(N,N-dimethylacrylamide)-based hydrogels, as well as efficacy testing services for hydrogel samples.
Process of Our Service
Want to Learn More?
As a leader in hydrogel development, Matexcel is well-versed in helping customers solve all their problems in poly(N,N-dimethylacrylamide)-based hydrogel development. Currently, we have successfully established an efficient and comprehensive technology platform to provide one-stop services from hydrogel raw material preparation and formulation customization to hydrogel analysis and characterization. If you are interested in our services, please fill out the online inquiry form and tell us more about your project.
Reference
- Shahid Bashir., et al. Flexible and self-healable poly (N, N-dimethylacrylamide) hydrogels for supercapacitor prototype. Colloids and Surfaces, A. Physicochemical and Engineering Aspects. 2021, 617:126377-.