Gelatin-Based Hydrogel Development Services

Due to its outstanding biocompatibility, transparency, modifiability, non-toxicity, and excellent mechanical properties that mimic the extracellular matrix (ECM), the gelatin-based hydrogel is considered to be an extraordinary multifunctional biomaterial with applications in a wide range of fields such as biomedicine and agriculture. As a hydrogel development specialist, Matexcel is committed to providing professional and efficient custom development services for gelatin-based hydrogels to our global customers. We look forward to collaborating with our customers to explore the potential of gelatin-based hydrogel applications.

Introduction to Gelatin-Based Hydrogel

A polydisperse protein, gelatin is produced by the irreversible hydrolysis of collagen fibrils into polypeptides with lower molecular weights. Although gelatin is chemically similar to the parent collagen, it has better solubility and less antigenicity. Meanwhile, Gelatin is considered an extremely promising candidate for use as a hydrogel component due to its hydration properties such as swelling and solubility. A typical property of gelatin solutions is the ability to form hydrogels by cooling at low temperatures (~20-30 °C). During the gelation process, locally ordered regions among the gelatin molecules take place, that is subsequently joined by non-specific bonds, such as electrostatic, hydrophobic bonds and hydrogen. Since the non-specific bonds are easily broken by heating, the resulting hydrogels have unique thermo-reversible (i.e., thermosensitive or thermally responsive) properties. In addition, the chemical and mechanical properties of the gelatin-based hydrogel can be modified by using different cross-linking agents (e.g., dextran dialdehyde, genipin, and glutaraldehyde) to give it better functional properties for different application scenarios.

Fig. 1 Schematic presentation of the preparation procedure for gelatin-based hydrogel electrodes. (Lee Y., et al., 2020)

Applications of Gelatin-Based Hydrogel

Gelatin-based hydrogel has many beneficial properties that make it an attractive polymeric material for a wide range of applications in biomedical and agricultural fields.

Our Services

Matexcel leverages our advanced technology and extensive experience in hydrogel development to help our customers break through all the challenges in gelatin-based hydrogel research and development. Our customized gelatin-based hydrogel development services include, but are not limited to, the following.

• Gelatin-Based Hydrogel Formulation Design Services: We provide customized gelatin-based hydrogel formulation design services to adjust the polymer concentration, cross-linking method, photoinitiator concentration, reaction temperature, pH and other conditions of the hydrogel according to the different requirements of downstream applications for the mechanical and functional properties of gelatin-based hydrogels.
• Gelatin-Based Hydrogel Modification Services: We can develop tailor-made modification solutions to modify and optimize the original properties of gelatin-based hydrogel for better performance, such as increasing the rheological properties or extending the degradation time of gelatin-based hydrogel, depending on the downstream application requirements for various performance parameters.
• Gelatin-Based Hydrogel Analysis and Characterization Services: We provide a full range of analysis and characterization services in the development of gelatin-based hydrogels, as well as efficacy testing services for gelatin-based hydrogel samples.

Process of Our Service

Want to Learn More?

With extensive and trusted experience and renowned experts, Matexcel is confident to provide our customers with highly comprehensive and efficient gelatin-based hydrogel development services. If you are interested in our services, please fill out the online inquiry form and tell us more about your project.

References

1. Liu C.; et al. Gelatin-based hydrogels with b-cyclodextrin as a dual functional component for enhanced drug loading and controlled release. RSC Advances. 2013, 3:25041-25049.
2. Jaipan, P.; et al. Gelatin-based hydrogels for biomedical applications. MRS Communications. 2017, 7(3):416-426.
3. Lee Y.; et al. Self-Adherent Biodegradable Gelatin-Based Hydrogel Electrodes for Electrocardiography Monitoring. Sensors (Basel). 2020, 20(20):5737.