Elastin-Based Hydrogel Development Services
Due to its unique physical and biological properties, including bioactivity, elastic resilience, structural stability and self-assembly ability, elastin is a reliable and efficient biomaterial for engineering elastic tissues and is widely used in the manufacture of functional hydrogel materials. As a leader in hydrogel research and development, Matexcel is committed to providing professional and efficient customized elastin-based hydrogel development services to our customers worldwide. We look forward to working with you to advance the application of elastin-based hydrogels in a wide range of fields.
Introduction to Elastin-Based Hydrogel
Elastin, one of the main elastomeric proteins in extracellular matrix (ECM), is present in the elastic fibers of the connective tissue, lung, cartilage, vessel, skin, ligament, and tendon, providing them with elasticity properties. Based on their self-assembly and phase transition behavior, elastin and elastin-like polypeptides (ELPs) are widely used for the development of hydrogel materials. ELP hydrogels have a biologically relevant elastic modulus that matches the soft tissue and can be adjusted according to the range of soft tissue stiffness, making them well suited for tissue engineering to develop robust scaffolds. However, due to its special structural characteristics, elastin is an extremely insoluble protein, and therefore this has become an important bottleneck in the development of elastin-based biomaterials. Based on this, more solutions should be explored to exploit the stronger application potential of elastin-based hydrogel.
Fig. 1 Synthesis of the elastin-based polymeric hydrogels. (Anika M., et al., 2012)
Applications of Elastin-Based Hydrogel in the Biomedical Field
Elastin-based hydrogel has many beneficial properties that make it an attractive polymeric material for a wide range of applications in biomedical fields.
- Used for tissue engineering applications to develop robust and durable tissue scaffolds.
- Used to develop shape memory hydrogels that contribute to biomedical applications.
- Used to develop bioactive elastin-based hydrogels that recruit and modulate innate immune cells to promote wound healing.
- Used in controlled drug release.
Our Services
Matexcel leverages our advanced technology and extensive experience in hydrogel development to help our customers break through all the challenges in elastin-based hydrogel research and development. Our customized elastin-based hydrogel development services include, but are not limited to, the following.
- Elastin-Based Hydrogel Formulation Design Services: We provide customized elastin-based hydrogel and ELP hydrogel formulation design services to adjust the polymer concentration, cross-linking method, reaction temperature, pH and other conditions of the hydrogel according to the different requirements of downstream applications for the mechanical and functional properties of hydrogels.
- Elastin-Based Hydrogel Modification Services: We can develop tailor-made modification solutions to modify and optimize the original properties of elastin-based hydrogels and ELP hydrogels, such as improving their mechanical properties and biological capabilities, according to the requirements of various performance parameters for downstream applications.
- Elastin-Based Hydrogel Analysis and Characterization Services: We provide a full range of analysis and characterization services in the development of elastin-based hydrogels and ELP hydrogels, as well as efficacy testing services for hydrogel samples.
Process of Our Service
Want to Learn More?
As a reputable expert in hydrogel development, Matexcel has successfully established a comprehensive development and service system to ensure comprehensive, efficient and cost-effective elastin-based hydrogel development services for our customers. If you are interested in our services, please fill out the online inquiry form and tell us more about your project.
References
- Anika M.; et al. Peptide- and Protein-Based Hydrogels. Chemistry of Materials. 2012, 24(5):759-773.
- Desai MS.; et al. Elastin-Based Rubber-Like Hydrogels. Biomacromolecules. 2016, 17(7):2409-16.