Alginate-Based Hydrogel Development Services
Alginate has extremely promising development and application prospects due to its excellent biosafety and functional properties. Currently, alginate-based hydrogels are widely used in applications such as tissue engineering, drug delivery, wound healing and cell culture. Matexcel leverages our expertise and experience in the field of hydrogels to help our customers overcome all the challenges encountered in the research and development of alginate-based hydrogels. We also support the large-scale production of alginate-based hydrogels to meet the growing demand for their applications in a wide range of fields.
Introduction to Alginate-Based Hydrogel
Alginate is a generic nomenclature for a family of linear polysaccharides such as alginic acid and alginate salts that are biocompatible, non-immunogenic, non-toxic, and have the properties of easily forming hydrogels and readily modifiable. Depending on the method of synthesis, alginate-based hydrogels can be classified as "physical" or "reversible" gels, and "chemical" or "permanent" gels. Many methods have been used to prepare alginate-based hydrogels, including ionic cross-linking, phase transition (thermal gelation), covalent crosslinking, cellular crosslinking, and free radical polymerization. According to the different needs in practical applications, specific chemical or physical methods of modification can be used to control certain properties of alginate-based hydrogels, such as mechanical hardness, swelling, degradation, cell attachment, and binding or release of bioactive molecules. However, the application potential of alginate-based hydrogels has not been fully exploited yet, thus there is an urgent need to invest more efforts in the research and development of new alginate-based hydrogels to make them play a more active role in various fields.
Fig. 1 Schematic of tubular hydrogel production. (Antunes M, et al., 2022)
Applications of Alginate-Based Hydrogel
Alginate-based hydrogels have many beneficial properties that make them attractive polymeric materials for a wide range of applications such as the biomedical field and medical devices.
Fig. 2 Benefits of alginate-based hydrogel for biomedical applications.
| Fields | Applications |
|---|---|
| Biomedicine |
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| Medical Devices |
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Our Services
Matexcel offers our expertise and advanced technology to help our customers develop alginate-based hydrogel development strategies to achieve efficient production of alginate-based hydrogels. Our scientists can develop customized optimization strategies based on our customers' requirements for alginate-based hydrogels production and downstream applications. Our customized alginate-based hydrogel development services include but are not limited to the following:
- Hydrogel formulation design services: We customize alginate-based hydrogels designs based on our customers' needs by varying hydrogel composition, cross-linking methods, configuration dimensions, permeability, aqueous liquid swelling, diffusivity, and degradability to precisely meet customer requirements for a variety of exciting and high-growth applications.
- Hydrogel modification services: Depending on the physicochemical properties of the alginate-based hydrogels, we select appropriate methods such as chemical grafting and physical blending to modify and optimize the original properties of the hydrogel to give it new excellent properties, such as excellent biocompatibility, degradability, easily adjustable physicochemical properties and structure.
- Hydrogel analysis and characterization services: We provide a full range of analysis and characterization services in the development of alginate-based hydrogels, as well as efficacy testing services for alginate-based hydrogel samples.
Process of Our Service
Want to Learn More?
Matexcel is committed to helping our customers overcome all difficulties in the alginate-based hydrogel research and development process. If you are interested in our services, please fill out the online inquiry form and tell us more about your project.
References
- Antunes M; et al. Development of alginate-based hydrogels for blood vessel engineering. Biomater Adv. 2022, 134:112588.
- Reig-Vano B; et al. Alginate-based hydrogels for cancer therapy and research. Int J Biol Macromol. 2021, 170:424-436.